Research on LNS for prevention

Randomized comparison of 3 types of micronutrient supplements for home fortification of complementary foods in Ghana: effects on growth and motor development. (abstract and free full-text)
Adu-Afarwuah S, Lartey A, Brown KH, Zlotkin S, Briend A, Dewey KG. Am J Clin Nutr. 2007 Aug;86(2):412-20.

Randomized controlled trial to test the effect of three different approaches for home-fortification of complementary food (multi-micronutrient powder, LNS and a crushable micronutrient tablet) on child growth (between 6 and 12 months of age) and motor development in Ghana.

Home fortification of complementary foods with micronutrient supplements is well accepted and has positive effects on infant iron status in Ghana. (abstract and free full-text)
Adu-Afarwuah S, Lartey A, Brown KH, Zlotkin S, Briend A, Dewey KG. Am J Clin Nutr. 2008 Apr;87(4):929-38.

Randomized controlled trial to test the acceptability and effect of three different approaches to home-fortification of complementary food (multi-micronutrient powder, LNS and a crushable micronutrient tablet) on micronutrient status (iron and zinc) and anemia in Ghanaian children between 6 and 12 months of age.

Breast milk intake is not reduced more by the introduction of energy dense complementary food than by typical infant porridge. (abstract and free full-text)
Galpin L, Thakwalakwa C, Phuka J, Ashorn P, Maleta K, Wong WW, Manary MJ. J Nutr. 2007 Jul;137(7):1828-33.

Randomized controlled trial to assess the effect of providing LNS as a complementary food on breast-milk intake in 6-month old infants as compared to a micronutrient-fortified maize-soy flour (likuni phala) used in Malawi for complementary feeding.

Effect of preventive supplementation with ready-to-use therapeutic food on the nutritional status, mortality, and morbidity of children aged 6 to 60 months in Niger: a cluster randomized trial. (abstract and free full-text)
Isanaka S, Nombela N, Djibo A, Poupard M, Van Beckhoven D, Gaboulaud V, Guerin PJ, Grais RF. JAMA. 2009 Jan 21;301(3):277-85.

Cluster-randomized controlled trial that evaluated the effect of providing three months of LNS (RUTF) to 6-60 month-old children in Niger on the prevention of moderate and severe wasting during an 8-month follow-up period.

An energy-dense complementary food is associated with a modest increase in weight gain when compared with a fortified porridge in Malawian children aged 6-18 months. (abstract and free full-text)
Lin CA, Manary MJ, Maleta K, Briend A, Ashorn P. J Nutr. 2008 Mar;138(3):593-8.

Randomized comparison of the effects of a peanut-/soy-based LNS and a corn porridge fortified with fish powder as complementary foods on growth and micronutrient status (zinc and selenium) in rural Malawian children between 6 and 18 months of age.

Complementary feeding with fortified spread and incidence of severe stunting in 6- to 18-month-old rural Malawians. (abstract and free full-text)
Phuka JC, Maleta K, Thakwalakwa C, Cheung YB, Briend A, Manary MJ, Ashorn P. Arch Pediatr Adolesc Med. 2008 Jul;162(7):619-26. Erratum in: Arch Pediatr Adolesc Med. 2008 Oct;162(10):942.

Randomized-controlled trial that compared supplementation for 12 months with LNS or a micronutrient-fortified maize-soy flour (likuni phala) on child growth and incidence of malnutrition between 6 and 18 months of age.

Postintervention growth of Malawian children who received 12-mo dietary complementation with a lipid-based nutrient supplement or maize-soy flour. (abstract)
Phuka JC, Maleta K, Thakwalakwa C, Cheung YB, Briend A, Manary MJ, Ashorn P. Am J Clin Nutr. 2009 Jan;89(1):382-90.

Follow-up study of Malawian children at 36 months of age to assess the long-term impact on growth and incidence of malnutrition from exposure to 12-months of supplementation with either LNS or a micronutrient-fortified maize-soy flour (likuni phala) between 6 and 18 months of age.